Lab Covers:
Key Papers:
Robertson CD, Richardson RR, Steyert M, Martin CA, Flynn C, Poulopoulos A. Prime Editing of Mouse Primary Neurons. Methods in Molecular Biology (2025) 2910:69-84.
Romanowski AJ, Richardson RR, Plachez C, Erzurumlu RS, Poulopoulos A. Gene Knockout in the Developing Brain of Wild-Type Rodents by CRISPR In Utero Electroporation. Methods in Molecular Biology (2025) 2910:221-238.
Brandenburg C, Poulopoulos A. Sparse Labeling, Rapid Clearing, and Native Fluorescence Light Sheet Imaging in the Developing Rodent Cerebellum. Methods in Molecular Biology (2025) 2910:263-276. (cover)
Altas B, Tuffy LP, Patrizi A, Dimova K, Soykan T, Brandenburg C, Romanowski AJ, Robertson CD, Khim SN, Bunce GW, Ambrozkiewicz MC, Yagensky O, Krueger-Burg D, Hammer M, Hsiao HH, Laskowski PR, Dyck L, Puche AC, Sassoè-Pognetto M, Chua JJE, Urlaub H, Jahn O, Brose N, Poulopoulos A. Region-Specific Phosphorylation Determines Neuroligin-3 Localization at Excitatory versus Inhibitory Synapses. Biological Psychiatry (2024) 96(10):815-828. (cover)
Richardson RR, Steyert M, Khim SN, Crutcher GW, Brandenburg C, Robertson C, Romanowski AJ, Inen J, Altas B, Poulopoulos A. Enhancing precision and efficiency of Cas9-mediated knockin through combinatorial fusions of DNA repair proteins. CRISPR Journal (2023) 6(5):447-461. (cover)
Blatt GJ, Brandenburg C, Poulopoulos A. India ink to 3D imaging: The legacy of Dr. Deepak “Dee” N. Pandya and his influence on generations of neuroanatomists. Journal of Comparative Neurology (2023) 531(18):1875-1882. (cover)
Altas B, Romanowski AJ, Bunce G, Poulopoulos A. Neuronal mTOR Outposts: Implications for Translation, Signaling, and Plasticity. Frontiers in Cellular Neuroscience (2022) doi: 10.3389/fncel.2022.853634.
Poulopoulos A, Murphy AJ, Ozkan A, Davis P, Hatch J, Kirchner R, Macklis JD. Subcellular transcriptomes and proteomes of developing axon projections in the cerebral cortex. Nature (2019) 565(7739):356-360. (F1000 recommended)
Poulopoulos A, Soykan T, Tuffy LP, Hammer M, Varoqueaux F, Brose N. Homodimerization and isoform-specific heterodimerization of neuroligins. Biochemical Journal (2012) 446(2):321-30.
Poulopoulos A, Aramuni G, Meyer G, Soykan T, Hoon M, Papadopoulos T, Zhang M, Paarmann I, Fuchs C, Harvey K, Jedlicka P, Schwarzacher SW, Betz H, Harvey RJ, Brose N, Zhang W, Varoqueaux F. Neuroligin 2 drives postsynaptic assembly at perisomatic inhibitory synapses through gephyrin and collybistin. Neuron (2009) 63(5):628-42. (F1000 recommended)
Review Articles:
Ament SA, Poulopoulos A. “The Brain’s Dark Transcriptome: Sequencing RNA in distal compartments of neurons and glia“. Current Opinion in Neurobiology (2023) 81:102725.
Itoh Y, Poulopoulos A, Macklis JD. Unfolding the Folding Problem of the Cerebral Cortex: Movin’ and Groovin’. Developmental Cell (2017) 41(4):332-334.
Poulopoulos A. ‘‘Holistic’ synaptogenesis. Biochemical Society Transactions (2010) 38(2):511-5.
Collaborative Papers:
Kwak G, Grewal A, Slika H, Mess G, Li H, Kwatra M, Poulopoulos A, Woodworth GF, Eberhart CG, Ko H, Manbachi A, Caplan J, Price RJ, Tyler B, Suk JS. Brain Nucleic Acid Delivery and Genome Editing via Focused Ultrasound-Mediated Blood-Brain Barrier Opening and Long-Circulating Nanoparticles. ACS Nano (2024) doi: 10.1021/acsnano.4c05270.
Greig LC, Woodworth MB, Poulopoulos A, Lim S, Macklis JD. “BEAM: A combinatorial recombinase toolbox for binary gene expression and mosaic genetic analysis“. Cell Reports (2024) 43(8):114650.
Altas B, Rhee HJ, Ju A, Solís HC, Karaca S, Winchenbach J, Kaplan-Arabaci O, Schwark M, Ambrozkiewicz MC, Lee C, Spieth L, Wieser GL, Chaugule VK, Majoul I, Hassan MA, Goel R, Wojcik SM, Koganezawa N, Hanamura K, Rotin D, Pichler A, Mitkovski M, de Hoz L, Poulopoulos A, Urlaub H, Jahn O, Saher G, Brose N, Rhee J, Kawabe H. Nedd4-2-dependent regulation of astrocytic Kir4.1 and Connexin43 controls neuronal network activity. Journal of Cell Biology (2024) 223(1):e201902050.
Iffland PH, Everett ME, Cobb-Pitstick KM, Bowser LE, Barnes AE, Babus JK, Romanowski AJ, Baybis M, Elziny S, Puffenberger EG, Gonzaga-Jauregui C, Poulopoulos A, Carson VJ, Crino PB. NPRL3 loss alters neuronal morphology, mTOR localization, cortical lamination and seizure threshold. Brain (2022) 145(11):3872-3885.
Engmann AK, Hatch JJ, Nanda P, Veeraraghavan P, Ozkan A, Poulopoulos A, Murphy AJ, Macklis JD. Neuronal subtype-specific growth cone and soma purification from mammalian CNS via fractionation and fluorescent sorting for subcellular analyses and spatial mapping of local transcriptomes and proteomes. Nature Protocols (2022) 17(2):222-251.
Qadir H, Krimmel SR, Mu C, Poulopoulos A, Seminowicz DA, Mathur BN. Structural Connectivity of the Anterior Cingulate Cortex, Claustrum, and the Anterior Insula of the Mouse. Frontiers in Neuroanatomy (2018) 12:100.
A conformational switch in collybistin determines the differentiation of inhibitory postsynapses.
Soykan T, Schneeberger D, Tria G, Buechner C, Bader N, Svergun D, Tessmer I, Poulopoulos A, Papadopoulos T, Varoqueaux F, Schindelin H, Brose N. A conformational switch in collybistin determines the differentiation of inhibitory postsynapses. EMBO Journal, (2014) 33(18):2113-33.
Jedlicka P, Hoon M, Papadopoulos T, Vlachos A, Winkels R, Poulopoulos A, Betz H, Deller T, Brose N, Varoqueaux F, Schwarzacher SW. Increased dentate gyrus excitability in neuroligin-2-deficient mice in vivo. Cerebral cortex (2011) 21(2), 357-367.
Fotinopoulou A, Tsachaki M, Vlavaki M, Poulopoulos A, Rostagno A, Frangione B, Ghiso J, Efthimiopoulos S. BRI2 interacts with amyloid precursor protein (APP) and regulates amyloid beta (Abeta) production. Journal of Biological Chemisrty (2005) 280(35):30768-72.
Modulation of voltage-gated potassium channels in human T lymphocytes by extracellular glutamate.
Poulopoulou C, Markakis I, Davaki P, Nikolaou C, Poulopoulos A, Raptis E, Vassilopoulos D. Modulation of voltage-gated potassium channels in human T lymphocytes by extracellular glutamate. Molecular Pharmacology (2005) 67(3):856-67.
Publication list on Google Scholar
