Just out, our paper on the biology of a synaptic adhesion molecule critically implicated in autism, published in Biological Psychiatry!

This massive paper includes outstanding work from scientists and collaborators at the Max Planck Institute for Multidisciplinary Sciences in Germany, and the University of Turin in Italy. It includes some of the first ever imaging of human synapses (spot the cool cup-shaped presynaptic terminals nestled in the human brainstem ????!), and identifies a molecular mechanism that determines the synaptic localization and transmitter-specificity of Neuroligin-3 between excitatory and inhibitory synapses in the brain. Congrats to everyone involved, a great way to end the year!

Region-Specific Phosphorylation Determines Neuroligin-3 Localization to Excitatory versus Inhibitory Synapses

Calling all Neuroscientists!!!

Come check out all the PouLab posters at SfN 2023

Sunday pm session: “Genetic Techniques to Target and/or Manipulate Cells”, three back-to-back posters :

• VV22: Find out what the best tag is for labeling your protein by Knockin at Andrea Romanowski‘s poster
  https://www.abstractsonline.com/pp8/#!/10892/presentation/39783
• VV23: Learn about how some genes are resistant to CRISPR-activation at Ashley Marquardt‘s poster
  https://www.abstractsonline.com/pp8/#!/10892/presentation/39785
• VV24: Get to see Neuroligin 3 for the first time in the human brain and how it might be used against brain cancer at Ro Whitten‘s poster
  https://www.abstractsonline.com/pp8/#!/10892/presentation/39784

Monday am session “Animal Models of Epilepsy: Genetics and Pharmacology”:

• C57: Learn about an exciting new way to model individual epilepsy patients in mice using prime editing from Colin Robertson‘s poster
  https://www.abstractsonline.com/pp8/#!/10892/presentation/32416

Wednesday pm session “Mechanisms Underlying Axon Growth and Targeting”:

• B14: Hear about a strange non-coding RNA that is involved in axon growth and potentially regeneration at Garrett Crutcher‘s poster
  https://www.abstractsonline.com/pp8/#!/10892/presentation/33556

Celebrate neuroscience with us!!!