Cheryl Brandenburg

Cheryl Brandenburg, PhD

Postdoc, T32 fellow

Contact: cherylbrandenburg{at}

Lab space: HSF3 room 9130

Cheryl’s publications on Google Scholar

Cheryl’s research goals center around developing support for individuals with autism after having worked as an in-home therapist for children on the spectrum.  Her dissertation studies focused on postmortem autism brain tissue and uncovering circuit alterations across individuals.  The cerebellum and basal ganglia became her primary regions of interest and, as a postdoc, she is currently working to characterize the impact of autism-associated genes on the development of cerebellar circuitry.  To accomplish this, she has optimized techniques for CRISPR genome editing, cerebellar in utero electroporation, clearing and light sheet imaging of rodent brains to quantify Purkinje topography in a 3D space.  By understanding circuit and signaling alterations, Cheryl hopes to one day understand the cerebellum’s contribution to challenging sensorimotor behaviors in autism.

Supported by:

Posts featuring Cheryl:

PouLab at SfN 2022

Follow our science at the 4 PouLab posters at SfN 2022 in San Diego!

Cheryl Brandenburg on Monday morning (Y5):
Light sheet mapping of parvalbumin subtypes of Purkinje cells using in vivo CRISPR strategies

Colin Robertson on Monday afternoon (YY36):
Neural somatic genome editing in the brain for personalized patient models

Garrett Bunce and Ro Whitten on Wednesday morning (B31):
The novel gene Ganon-1 produces a scaffolding RNA for growth signaling in developing axon projections

Andrea Romanowski on Wednesday morning (C45):
Mosaic Cas9 fusions to investigate cortical wiring by IgLON schizophrenia risk-genes in the rodent brain”

See you all at #SFN2022

Dr. Cheryl Brandenburg receives SfN Trainee Professional Development Award!

See Cheryl’s light sheet-imaged Purkinje Cells in 3D and the rest of the lab’s research at #SfN2022 in San Diego!

Cheryl Brandenburg receives Autism Research Institute grant!

PouLab postdoc Cheryl Brandenburg was awarded a 2021 Autism Research Institute (ARI) grant for her work on “Cerebellar Circuits in 3D: Screening autism-associated genes in cleared brains with in utero CRISPR genome editing“. Congratulations Cheryl!!! Here is just a snippet of the mind-bending 3D cerebellar circuits from Cheryl’s in vivo edited Purkinje cells…!