Editing the Brain @ University of Maryland School of Medicine
Congrats to Colin Robertson and other lab members for publishing “Prime Editing of Mouse Primary Neurons” on how to use Prime editors on neurons to introduce precise genome edits, including pathological variants from patients.
This paper also includes a step-by-step guide on how to use our web app for pegRNA design and cloning PegAssist.app!
We should be hearing more exciting news from Colin and this powerful new technology for neural somatic genome editing soon…!
Corinne Martin, a rising sophomore majoring in Bioengineering at the University of Maryland, College Park, joined the lab as part of the Nathan Schnaper Intern Program in Translational Cancer Research (NSIP).
Corinne is working on the genetic intersections between neoplasia and brain development, mining patient genome databases and using in vivo genome editing to probe effects on brain circuit development.