Saovleak (Noury) Khim
Postbac, STAR-PREP Scholar
BSc, Cell & Molecular Neuroscience, Temple University
Lab space: Microscopy suite, HSF3 room 9168
Posts with Noury:
Phosphorylation of Neuroligin-3
Our work on how the synaptic adhesion molecule Neuroligin-3 is targeted to either excitatory or inhibitory synapses based on phosphorylation is now available on the bioRxiv! Congrats to Bekir Altas, Liam Tuffy, Annarita Patrizi and the rest of the team in this international collaboration between the University of Maryland School of Medicine, the Max Planck Institute for Multidisciplinary Sciences, and the University of Turin.
Phosphorylation Determines Whether Neuroligin-3 is at Excitatory or Inhibitory Synapses in Different Regions of the Brain
Getting creative to keep science strong in the pandemic
Noury Khim, unflinching scientist vs. the pandemic! Taking on the hurdles of social distancing, Noury live streams a procedure from a head mounted phone to train the lab’s incoming graduate students. To research and teach against all odds, you gotta be strong… #ScienceWomanStrong
Congrats to Ryan and co. for “Cas9 fusions for precision in vivo editing” out on the bioRxiv!
The lab’s first pub is a nifty piece of synth bio for genome editing the brain. Richardson et al. describe a platform to test and develop new high-precision genome editing reagents. Some of our new CRISPR fusions, like eRad18-Cas9-CtIP with linear donors, showed up to 45-times higher accuracy at point-mutation editing compared to vanilla CRISPR. Another step toward direct in vivo knockin and in situ gene therapy approaches!