Ryan’s article on advancing scientific excellence through inclusivity at the NIH BRAIN Initiative is out in Neuron!

Lab alum, Ryan R. Richardson, now a AAAS STP fellow at the NIH BRAIN Initiative, together with colleagues deputy Director Andrea C. Beckel-Mitchener, Director John Ngai, and program Director Devon C. Crawford, published a paper today in Neuron, outlining how BRAIN’s mission for scientific excellence is empowered by tapping into the full spectrum of diverse talents and perspectives. We’re grateful for your work in advancing opportunities and excelling innovative neuroscience research through inclusion and diversity!

https://www.cell.com/neuron/fulltext/S0896-6273(21)00836-9

Ryan R. Richardson

Corinne Martin joins the team as the lab’s first Nathan Schnaper Intern!

Corinne Martin, a rising sophomore majoring in Bioengineering at the University of Maryland, College Park, joined the lab as part of the Nathan Schnaper Intern Program in Translational Cancer Research (NSIP).

Corinne is working on the genetic intersections between neoplasia and brain development, mining patient genome databases and using in vivo genome editing to probe effects on brain circuit development.

Congrats to Bek and Alex for Postdoctoral Fellow Excellence in Mentorship and Teacher of the Year Awards!

Bek Altas and Alex Poulopoulos were Awarded by the Graduate School of Life Sciences with the 2020 Postdoctoral Fellow Excellence in Mentorship Award and Teacher of the Year Award, a lab dynamic duo in mentorship!!!

Congrats to Ryan and co. for “Cas9 fusions for precision in vivo editing” out on the bioRxiv!

The lab’s first pub is a nifty piece of synth bio for genome editing the brain. Richardson et al. describe a platform to test and develop new high-precision genome editing reagents. Some of our new CRISPR fusions, like eRad18-Cas9-CtIP with linear donors, showed up to 45-times higher accuracy at point-mutation editing compared to vanilla CRISPR. Another step toward direct in vivo knockin and in situ gene therapy approaches!

https://www.biorxiv.org/content/10.1101/2020.07.15.199620v1