PhD student, Program in Molecular Medicine
Lab space: In utero surgery suite, HSF3 room 9131
Posts with Andrea:
Congrats to Ryan and co. for “Cas9 fusions for precision in vivo editing” out on the bioRxiv!
The lab’s first pub is a nifty piece of synth bio for genome editing the brain. Richardson et al. describe a platform to test and develop new high-precision genome editing reagents. Some of our new CRISPR fusions, like eRad18-Cas9-CtIP with linear donors, showed up to 45-times higher accuracy at point-mutation editing compared to vanilla CRISPR. Another step toward direct in vivo knockin and in situ gene therapy approaches!
The Lab goes to Chicago…
(photo by T. Soykan)
The lab has fun recreating Raphael’s “The School of Athens” in Chicago, while presenting at the 2019 meeting of the Society for Neuroscience!
Ryan, Marilyn, and Jeffrey unveiled their new approach to high efficiency in vivo genome engineering with in situ CRISPR:
Bek, Andrea, Noury, and Uriel debuted their findings on how a mutation in a family with intellectual disability affects the dynactin complex and cortical circuit wiring:
Alex presented new findings on how phosphorylation of Neuroligin adhesion molecules determines synapse specificities:
And how reciprocal adhesion gradient matching guides the development of cortical circuitry:
… and Garrett stashed us some sweet top-shelf probes…
Congratulations to Andrea Romanowski for passing her qualifying exam and advancing to PhD candidacy with flying colors!
The lab does Baltimore Brain Awareness Week
Andrea and Garrett spreading the love for neuroscience at Windsor Hills Elementary and Middle School!
Learn more at UMB NOVA (Neuroscience Outreach and Volunteer Association)
New lab rotation students get the window chalk talk
Do we use the windows as white boards? We sure do.
Today is the first day for Ben Grosso (Program in Biochemistry & Molecular Biology) and Garrett Bunce (Program in Neuroscience) in the lab, kicking off the first round of 2019 lab rotations for GPILS students. Andrea and Marilyn introduce the new lab members to the lab’s science…