The lab’s first pub is a nifty piece of synth bio for genome editing the brain. Richardson et al. describe a platform to test and develop new high-precision genome editing reagents. Some of our new CRISPR fusions, like eRad18-Cas9-CtIP with linear donors, showed up to 45-times higher accuracy at point-mutation editing compared to vanilla CRISPR. Another step toward direct in vivo knockin and in situ gene therapy approaches!
Moving day is here! Time for the Poulopoulos Lab to get a new home across the street in Health Sciences Facility III.
Equipment needs bubble wrap, heavy things need lifting, scopes come apart and back together again. And in the midst of this madness, our science doesn’t miss a beat! The heroic investigators of the lab continued cloning and perfusing in between filling crates and hauling off incubators. Everyone working hard… except the guy behind the camera, that is.
Goodbye old lab… hello vista from the 9th floor of the new and improved PouLab!!!